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Peter de Boves Harrington, Director of the Center for Intelligent Chemical Instrumentation Ohio University, delivers a speech at WEIS 2013 |
2013/11/22 |
Peter de Boves Harrington, Director of the Center for Intelligent Chemical Instrumentation Ohio University, delivers a speech at Track C World Forum on Intelligent Manufacturing Industry of the 2nd WORLD EMERGING INDUSTRIES SUMMIT (WEIS 2013) Outline of the speech: • Smarter Products Based on Chemical Sensing • Peter de B. Harrington, PhD • OHIO University, Center for Intelligent Chemical Instrumentation • Short Definition of Terms • Forensics is an application area of science applied to solving legal problems. • Proteomics is the study of protein profiles and networks and can be applied to medicine and curing disease. • Chemometrics is the study of maximizing the information gained from making chemical measurements. • Embedded and automated chemometric methods are required for smart instruments and chemical sensors. • The Future is Now • Advances in micro-machined electronics and instruments affords the opportunity for low-cost disposable chemical sensors. • Sensors can be embedded into many household and industrial products to improve the quality of life and ensure health and safety. • Chemical Sensing • Just as we have 5 senses; hearing, sight, smell, taste, touch • Analytical instruments can provide chemical profiles • Profiles are lists of chemicals and their amounts – Air we breathe – Food we eat – Health of our bodies • Smart Undergarments • Smart Sensors These instruments have built in knowledge so anyone can use them. Smart Buildings • Healthy People • The use of chemical instruments can be used to profile – Proteins in bodily fluids – Small molecules in breathe, saliva, urine • These chemical profiles can be used to detect diseases such as cancer • Detect the presence of toxins or drugs • Monitor overall health such as blood sugar for diabetics • Authentication is Important for Food Safety • Authentication is the act of validating the identity of a material usually with respect to the product label or description – Composition – Source $3,400,000 – Purity – Age • Important for detection of adulteration, spoilage, contamination, and mislabeling • Safe Foods • In a study organized by the US Pharmacopeia 117 skim milk samples and 702 skim milk samples that were adulterated with vegetable proteins were profiled using MALDI-MS. • The level of adulteration ranged from 5% to 0.1%. • The adulterated samples could be detected with 100% accuracy from the unadulterated samples. • These methodologies could enable producers to protect their products and provide consumer assurance. • Conclusion • Smart chemical sensors can improve our quality of life • Chemometrics provides the tools to make the sensors smart by providing algorithms that convert data to information. • These algorithms are embedded, automated, and invisible to the users. • Several tools for the automated processing of chemical profiles into information streams have been developed. – Fuzzy Rule-building Expert Systems (FuRES), Harrington, 1991. – Fuzzy Optimal Associative Memories (FOAM), Harrington, 1996. – Principal Component Orthogonal Signal Correction (PC-OSC), Harrington, 2009. |
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